the artificial
digestive neuron
OBESITY: 16.9% of adult population is overweight
more than 30% of the population is affected by weight problems*
6.5% of the population is affected by DIABETES*
7% of adult population is affected by GERD*
HEART DISEASES: 117 deaths per 100,000 people caused by ischemic heart disease,54 deaths per 100,000 people due to stroke*
HEART DISEASES: 117 deaths per 100,000 people caused by ischemic heart disease, 54 deaths per 100,000 people due to stroke*
PSORIASIS: from 2 to 3% of the population is subject to psoriasis*
DEPRESSION: the costs related to the depression syndrome
are on average 10% of total health care costs*
10% of adult population is affected by CONSTIPATION*
Phoenix: the BNM

Device under experimental investigation


Diseases like obesity, gastro-esophageal reflux disease (GERD), high resting heart rate, type 2 diabetes, and others are important unsolved problems spreading worldwide. Poor life quality, high treatment costs, negative side effects and no definitive solutions are the unfortunate problems of functional digestive diseases.


Many years of clinical activity in the field of gastric pacing on obese patients led Dr. Valerio Cigaina to discover that digestive functional diseases are characterized by an abnormal sympathetic tone in the autonomous nervous system (ANS). This abnormality was not a consequence of the disease itself, but exactly the opposite: the unbalanced ratio between sympathetic and parasympathetic components of the nervous system is the main cause of the pathologic situation. The neurological stimulation initially obtained by the gastric pacemaker had great effects on obese patients. In addition to weight loss, symptoms of associated diseases such as hyperglycemia in type 2 diabetes, diastolic hypertension, gastro-esophageal reflux, etc. were reduced or completely solved. Dr. Cigaina used the term “neuromodulation” because he discovered that a dedicated electrical stimulation of particular areas of the stomach modifies the natural balance of the resting autonomic nervous system.
A reduced sympathetic/parasympathetic ratio can dramatically improve several functional diseases and consequently quality of life.
Our path-breaking device, the Brain Neuromodulator (BNM) provides an alternative method of neuromodulation than gastric pacing to address digestive functional diseases. The BNM has significant advantages over existing devices. It does not require surgery and therefore is much safer, less invasive and less expensive than the alternatives. The BNM does not involve a wire and does not need a battery. As it is implanted in the wall of the stomach, there are no risks of the device being dislodged. Finally, the BNM can be removed, if necessary, with an endoscopy procedure, as first choice.
MedAutonomic Inc. - 1235 Traud Drive - Concord CA - 94518 USA -
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